Sunday sees the first Wear-Tyne derby after 2024, but who will emerge victorious – Sunderland or Newcastle?
"For most of last season, you couldn't have imagined Sunderland getting promoted and holding their own with Eddie Howe's Newcastle, never mind being above them in the table," commented football expert Chris Sutton.
"The situation is very different now, and the way they play makes me think they've got a real chance."
Sutton is making scoreline guesses for all 380 Premier League games this season, in competition with AI, the public and a range of guests.
For the upcoming matchday, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the eLions – the Football Association's official esports team – at the EA Sports FC digital Euros finals tournament, which will occur at Twickenham Stadium on Saturday.
Viewers can catch Uefa's YouTube, IG Live and TikTok channels, as well as the official Twitch channel and its YouTube counterpart and the national team's Twitch.
Do you agree with their forecasts? Share your own predictions below.
The fan-favourite scoreline picked for each game is featured in the scoreboards at the bottom of this page.
A correct result (selecting a win, draw or defeat) is worth ten points. A perfect prediction earns forty points.
Ray, who also plays Gen City and Manchester City as well as England, is competing for the first time at the eEuros finals after passing the qualification rounds.
Eight players will represent their nations at the finals in a knockout format, vying for a six-figure prize fund and a highly sought-after spot in the FC Pro World Championship Play-Ins, with the Danish representative Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray remarked. "I have a really good coach with me and training has been going well.
"It is invariably an honour to play for your country. Naturally when you are younger, you imagine doing it as an real-life footballer, but when you pursue a career in this job and there is an chance to represent England, donning the national jersey is something incredible.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"For me he is the number one in the world so beating him in a tournament like this just gives you a huge surge of confidence."
Stamford Bridge, 15:00 GMT
The London club were outstanding against Arsenal at the end of November, when they secured a point after going down to 10 men, and I was thinking they've turned a corner, they could possibly be challengers for the crown.
However, since that game, however, they were beaten physically by Leeds, looked uninspired against Bournemouth and this week got turned over by Atalanta in the Champions League.
So manager Enzo Maresca is in need of a win here to return to winning ways, but it won't be easy because Everton are such a potent team.
Two of their stars are playing at the top of their game and they have got a bit of form at the moment.
Based on recent performances you would likely back the visitors, while the most prudent prediction would likely be a draw, but I'm throwing caution to the wind.
The Blues have failed to given me any good cause to back them recently, but I just have a feeling they will take this one because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Anfield, 15:00 GMT
I'm attending this game and it will be intriguing to see what we get from the Reds.
It was great to see for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday after all the controversy with Mohamed Salah this week.
Slot ought not to put up with that distraction. I know Salah has been a legend for Liverpool but at its core Slot just wants to win games and there is no ulterior motive in his team selection.
They changed their shape against Inter and went with a midfield diamond and two up top.
Everyone is going to be talking about whether Salah is selected for this game, but the only way he is going to be brought back into the fold is if he apologises.
Slot's focus will be on winning this game, but it is a challenging encounter.
One might suggest it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are vulnerable at the back too.
Liverpool need to get back to stringing wins together, but I am not sure how much their efforts at the San Siro will have drained them.
I put a couple of Brighton players in my Fantasy Premier League side, so they will almost certainly blank - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Stadium of Light, 14:00 GMT
The Wearside club have had the opportunity to rest while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Aside from their excellent performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
It is anticipated that that trend to continue on Sunday, and their lack of freshness is likely to be a significant issue in how this game goes because of Sunderland's energetic style.
Their match against Arsenal demonstrated how unwavering Regis le Bris's side are. They dominated the Gunners, and it was incredible to watch.
Everyone talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been superb, but Noah Sadiki, who plays in midfield with him, has also been one of the best acquisitions and should be recognised too.
All signs point to this being the best game|most exciting fixture
Eva is een ervaren ondernemerscoach en schrijft over zakelijk succes in Almere.